Fig. 8 | Nature Communications

Fig. 8

From: Bioconjugation strategy for cell surface labelling with gold nanostructures designed for highly localized pH measurement

Fig. 8

Visualization of AuNP anchored to the cell membrane by SERS. Typical results of SERS spectral intensity as collected from a z-axis line scan performed in the middle of a MKN28 cell after AuNP anchoring. The intensities in the range 925–1230 cm−1 are shown as a function of the position along the z-axis. The z = 0 position corresponds to the bottom of the cell, which was identified by focusing the laser on the glass bottom dish. The symmetric shape of the SERS intensity distribution of each band along the z-axis confirms the location of the nanometer pH sensor in one single position, namely the point of maximum intensity at z = 12

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