Fig. 2 | Nature Communications

Fig. 2

From: Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

Fig. 2

Lack of AEP induces an increase in the hydrolytic capacity of lysosomes in vivo. Heatmap built using heatmap.2 in the gplots package of R program showing proteins over-represented (red) or under-represented (green) in the AEP−/− lysosomal kidney fractions compared to WT samples as identified by our SILAC approach, organised by cellular location and molecular function

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