Table 1 Definitions of each transmission scenario and the parameters estimated from the data

From: The utility of serology for elimination surveillance of trachoma

Model name

Transmission assumption

λ T

λ UG

ρ

t c

γ

Scenario 1v1

Constant

Yes

No

Yes

No

No

Scenario 1v2

Constant

Yes

No

No

No

No

Scenario 2v1

Fixed change point

Yes

No

Yes

Yes

Yes

Scenario 2v2

Fixed change point

Yes

No

No

Yes

Yes

Scenario 2v3

Fixed change point

Yes

Yes

Yes

Yes

Yes

Scenario 2v4

Fixed change point

Yes

Yes

No

Yes

Yes

Scenario 3v1

Linear decline

Yes

No

Yes

No

Yes

Scenario 3v2

Linear decline

Yes

Yes

Yes

No

Yes

Scenario 3v3

Linear decline

Yes

No

No

No

Yes

Scenario 3v4

Linear decline

Yes

Yes

No

No

Yes

  1. For each scenario we indicate with a yes or a no as to whether or not a given parameter was estimated from the data for that scenario. The parameters listed are defined as follows: λT (Rate of sero-conversion due to exposure to trachoma), λUG (Rate of sero-conversion due to exposure to urogenital infection), ρ (Rate of sero-reversion), tc(Fixed time point at which transmission intensity changed), γ (Proportional decline in transmission at tc or over time). Note that the interpretation of γ for scenario 2 and 3 are different. For scenario 2, it is the ratio between average transmission rates of two time intervals. For scenario 3, it is the ratio between two end points of the whole study period