Fig. 3 | Nature Communications

Fig. 3

From: Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Fig. 3

Two-sample MR of eGFR on calculus of kidney and ureter. Results are presented separately for each component of the trans-ethnic meta-analysis. Each point corresponds to a lead SNV (instrumental variable) across 94 kidney function loci, plotted according to the MR effect size of eGFR on calculus of kidney and ureter (Wald ratio). Bars correspond to the standard errors of the effect sizes. The red point and bar in each plot represents the MR effect size of eGFR on calculus of kidney and ureter across all SNVs under inverse variance weighted regression. The p-values are obtained under inverse variance weighted regression. Results for other methods are presented in Supplementary Table 8

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