Fig. 7

Deletion of Ckip-1 in hematopoietic cells is responsible for the increased atherosclerosis in Apoe^−/− Ckip-1^−/− mice. a Bone marrow transfers were performed in 6-week old lethally irradiated Apoe^−/− and Apoe^−/− Ckip-1^−/− mice followed by reconstitution with bone marrow from Apoe^−/− or Apoe^−/− Ckip-1^−/− mice, respectively. Representative images of Oil Red O-stained aortas of each group chimeras and quantification of lesion area are shown, n = 9. b Representative images of cross-sections of the aortic roots from each group stained with H&E and quantification of aortic root lesion area are shown. Scale bar, 500 μm. n = 5. Data represent mean ± s.e.m. P values were calculated by two-tailed Student’s t-test (a, b). *P < 0.05, **P < 0.01, ***P < 0.001. The precise P value and statistics source data are in Supplementary Data 2