Fig. 2 | Nature Communications

Fig. 2

From: Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

Fig. 2The alternative text for this image may have been generated using AI.

Gut bacteria harboring tyrosine decarboxylases are responsible for levodopa decarboxylation. a Aligned genomes of E. faecium, E. faecalis, and L. brevis. The conserved tdc-operon is depicted with tdc gene in orange. Overnight cultures of b E. faecalis v583, c E. faecium W54, and d L. brevis W63 incubated anaerobically at 37 °C with 100 µM of levodopa (LD). e Overnight cultures of EFSWT and EFSΔTDC incubated anaerobically at 37 °C with 100 μM levodopa (black line) compared to control (gray line) where no levodopa was added. Curves represent one example of three biological replicates

Back to article page