Fig. 4
From: Mitotic chromosome binding predicts transcription factor properties in interphase
Mitotic chromosome binding predicts genome-wide TF occupancy. a Correlation between the number of ChIP-seq peaks called and the ψon-rate for 8 different TFs. r-value (r) and p-value (p) are based on Pearson correlation. b Correlation between the number of ChIP-seq peaks called and TF relative residence times for 8 different TFs. r-value (r) and p-value (p) are based on Pearson correlation. c Genome tracks of RPKM-normalized bigWig files for each TF. The region encompasses the entire chromosome 19. The y-axis is scaled equally for all factors. d Correlation between the mitotic bound fraction and the number of ChIP-seq peaks called. Duplicates are indicated for OCT4 (yellow), SOX2 (green), BHLHB8 (red), and FOXA1 (dark blue). The two FOXA1 mutants are shown in light blue. Triangles TFs endogenously expressed in NIH-3T3. Circles: TFs not endogenously expressed in NIH-3T3. Rho-value (Rho) and p-value (p) are based on Spearman’s rank correlation. e Correlation between the mitotic bound fraction and the number of ChIP-seq peaks displaying the most frequently found motif for each TF, normalized over the total number of motif occurrences in the genome. Same color and shape coding as d. Rho-value (Rho) and p-value (p) are based on Spearman’s rank correlation. Error bars: SEM
