Fig. 3

Drug susceptibility testing and sequence analysis of resistant mutants. a Time-killing cures of TB47 (1 μg mL−1) against autoluminescent M. marinum resistant mutants (R1 to R7) and the parent strain in liquid culture. Data are expressed as mean ± SD from three independent biological repeats. The experiment was performed in triplicate (three independent experiments) and the representative results are shown. b Results of polymorphism in QcrB conferring resistance to TB47. WT, wild-type