Table 2 Frequency of each antigen being present in the most protective combinations
From: Targets of complement-fixing antibodies in protective immunity against malaria in children
Combination size: | Frequency of antigen in top 1% of combinations | |||
|---|---|---|---|---|
3 antigens | 4 antigens | 5 antigens | 6 antigens | |
RALP1 | 100% | 100% | 100% | 100% |
MSP7 | 72.7% | 66.7% | 65.2% | 64.6% |
Ripr | 36.4% | 62.5% | 85.8% | 99.2% |
EBA140RIII-V | 18.2% | 20.8% | 16.8% | 18.1% |
RH2–2030 | 18.2% | 25.0% | 32.9% | 39.5% |
MSP-DBL1 | 18.2% | 18.8% | 29.7% | 37.7% |
PfRH5 | 9.1% | 18.8% | 31.6% | 44.4% |
GAMA | 9.1% | 18.8% | 16.8% | 18.1% |
MSP1–19 | 9.1% | 18.8% | 19.4% | 26.4% |
EBA175RII | 9.1% | 25.0% | 32.3% | 35.1% |
MSP6 | 0% | 8.3% | 13.5% | 20.4% |
EBA175RIII-V | 0% | 2.1% | 6.5% | 9.6% |
MSP10 | 0% | 0% | 3.2% | 7.5% |
MSP2(3D7) | 0% | 2.1% | 11.0% | 15.0% |
MSP4 | 0% | 2.1% | 5.8% | 10.6% |
EBA140RII | 0% | 4.2% | 12.3% | 17.8% |
AMA1 | 0% | 2.1% | 8.4% | 14.5% |
MSP9 | 0% | 0% | 0.6% | 1.0% |
MSP3 | 0% | 4.2% | 8.4% | 19.9% |
Pf113 | 0% | 0% | 0% | 0.5% |