Fig. 9 | Nature Communications

Fig. 9

From: Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer

Fig. 9The alternative text for this image may have been generated using AI.

IHC staining of viable tumor after 10 Gy + anti-PD1 or IRE + anti-PD1. Representative micrographs of staining for CD31 (a), Picrosirius Red (b), αSMA (c), FAPα (d), HABP1 (e), and Ki67 (f) in control (black solid circle), 10 Gy + anti-PD1 (red diamond), and IRE + anti-PD1 (blue triangle) groups, and corresponding quantifications. Ten to fifteen visual fields were randomly captured. Scale bars = 50 µm. Five doses of anti-PD1 had been administered at this time point for the 10 Gy + anti-PD1 and IRE + anti-PD1 groups. Data are presented as mean ± SEM. Significance was determined using 1-way ANOVA followed by Tukey post hoc analysis. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. MFI mean fluorescence intensity, FOV field of view, n.s. not significant. Source data are provided as a Source Data file

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