Fig. 3

Transcriptomic, proteomic, and metabolomic analyses identified a robust trajectory of differentially expressed genes, proteins, and metabolites over the first week of life. a Up- and downregulated differentially expressed genes were plotted by DOL (vs. DOL0) and numbers of genes are listed above each point except for downregulated genes at DOL1 vs. DOL0, where the number was zero. b, c Up- and downregulated differentially expressed proteins and metabolites, respectively, plotted by DOL compared to DOL0, with numbers of differentially expressed proteins or metabolites listed above each point. d Zero-order interaction networks for genes differentially expressed at DOL3 vs. DOL0 and DOL7 vs. DOL0. Within networks, upregulated nodes are displayed in red and downregulated nodes in blue. DOL: day of life