Fig. 2
From: Orthobunyavirus spike architecture and recognition by neutralizing antibodies
The head and stalk domains form the trigonal pyramid of the OBV envelope. a–c Trimeric head domain assemblies as found in the crystal structures for a BUNV, b LACV, and c OROV. Trimers are shown in top view (top) and in side view (below). The threefold crystallographic axes are indicated as filled triangles (top views) and as vertical bars (side views). The three identical protomers are shown in blue, red, and white, respectively. Disulfide bonds are shown in bright green; carbohydrate chains are shown as white sticks. d Position of head and stalk within the electron cryo-tomography map of the BUNV glycoprotein spike17. The displayed model is composed of the trimeric BUNV head domain structure as in panel a and of the stalk from SBV as in Fig. 1b. The spike is shown in side view (left) and in top view (right). The two non-equivalent threefold symmetry axes within the local structure of the envelope are indicated as filled and empty triangles (right)
