Fig. 6

Open particle of echovirus 30. a, b Reference-free two-dimensional class averages showing echovirus 30 particles lacking parts of their capsids. For each class, average images of two representative particles are shown. c Three-dimensional reconstruction of open particle of echovirus 30 lacking one pentamer with imposed five-fold symmetry. The electron density map is rainbow colored based on the distance from the particle center. d Electron density distribution in central section of reconstruction of open particle. The diffuse density in the pore formed by the missing pentamer probably belongs to the average of RNA molecules escaping from the particles. Scale bars represent 10 nm