Fig. 6 | Nature Communications

Fig. 6

From: Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

Fig. 6

Construction of HMOP-TBHP/Fe(CO)5 and X-ray-activated CO release. a TEM image of HMOP-Fe(CO)5. Scale bar: 50 nm. b Elemental mapping (Si, O, Fe) of HMOP-Fe(CO)5. Scale bar: 50 nm. c EDS spectrum of HMOP-Fe(CO)5. d X-ray photoelectron spectroscopy (XPS) spectrum of HMOP-Fe(CO)5. e Binding energies of Fe(2P3/2) and Fe(2P1/2) correspond to 711 and 724 eV, respectively, indicating the attachment of Fe(CO)5 to HMOP. f Thermo-gravimetric (TG) curves of HMOP and HMOP-Fe(CO)5. g Schematic of X-ray-triggered CO release from HMOP-TBHP/Fe(CO)5. h Fluorescence spectra of COP-1 probe subjected to varied doses (0, 2, 4, and 6 Gy) of X-ray irradiation in the presence of HMON-Fe(CO)5 or HMOP-TBHP/Fe(CO)5. i Evaluation of CO generation based on the normalized fluorescence intensity of COP-1 probe at 520 nm

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