Fig. 1

Monitoring the propagation of transcriptional activity in proliferating cells. a A cell from the Rbpj reporter line progressing through two cell cycles. Luminescent cell nuclei are tracked manually. Scale bar: 10 μm. b Representation of events in a. c Schematic of the transcriptional activity profiles over cell lineages in genes with short or long memory. Two families with either high or low initial transcriptional activity with respect to the population average (dotted black line) are shown