Fig. 1 | Nature Communications

Fig. 1

From: Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance

Fig. 1

Identification of E2-induced compartments in MCF7 cells at T1 vs. T0. a Pearson correlation of two biological replicates with the bin size of 1 Mb, 500 Kb and 200 Kb on individual chromosomes at untreated MCF7 cells (T0) (Top) and E2-treated MCF7 cells for 1 h (T1) (Bottom). b Contacts matrices of compartment A (Black) and B (Red) at T0 (Top) and T1 (Bottom) respectively. c, d Histograms of compartments with different sizes at T0 and T1 respectively. e Distribution of compartments A and B in T0 and T1 respectively. f The percentage of common and transit compartments at T1 vs. T0 with various bin sizes. g The number of compartments of T1 vs. T0 with various shifted length when bin size is 100 Kb

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