Fig. 2
fUS detect a rule change from the single first trial. a The start of the first visual cue induced a strong CBV variation of ~40% in the SEF reached in 2.5 s (quantified in a large ROI delineated by a black line, ~240 pixels), and the CBV was already twofold greater than the standard deviation of baseline (σ) after 1.5 s. Whether CBV was quantified in a large ROI or in a 1-pixel ROI (pixel chosen with the highest variation of CBV over the experiment), the delay to observe CBV above a certain range of σ was similar (average over 85 acquisitions). b The CBV variation between the beginning of the first trial and 2.5 s after was highly significant in the SEF (in the large and 1-pixel ROI), whereas no difference was observed in the control region (paired-sample t-test). Raw data (red and green circles) were summarized with mean (solid black line), 95% confidence interval (light gray area), and one standard deviation (transparent gray area)
