Fig. 2 | Nature Communications

Fig. 2

From: Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Fig. 2

Identification of LCORL mutation in large breeds and comparison with human. a Comparison of genomic sequences between human and the two canine alleles. A single nucleotide insertion is observed in large breeds (>41 kg). b Conservation of the two main LCORL proteins and their predicted functional domain using SIM68 and LALNVIEW69. c Schematic representations of LCORL proteins, highlighting the effect of the canine mutation (STOP codon after amino acid 1221 leads to a loss of 610 aa). The common part shared by all forms is colored in yellow. Source data are provided as a Source Data file

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