Table 1 Transgenic expression of tRXRα promotes colorectal carcinogenesis

From: Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling

Model

DSS alone

AOM alone

Group of mice

WT

tRXRα

WT

tRXRα

Number of mice

12

8

1

1

6

4

2

Tumors of mouse

0

0

2

1

0

0

1

Mice with tumours

0

 

20%

 

0

33.4%

P value

0.05211

0.0607

  1. AOM azoxymethane, DSS dextran sodium sulfate, tRXRα trunacted retinoid X receptor α, WT wild type