Fig. 7
p110αDEL mice accumulate less weight with age. a, b Body weight gain over time in female (a) and male (b) p110αDEL and p110αFLOX mice. The average body weight of each group of mice between 8 and 26 months of age were compared by unpaired t test. n = 66 per genotype for male; n = 76 p110αFLOX and 58 p110αDEL for female. c Epididymal WAT and interscapular BAT mass of 1.5- and 2-year-old male mice. n = 10 per genotype for WAT; n = 8 per genotype for BAT. d Food intake of approximately 1-year-old mice. Each data point represents an average measurement from a single cage. Female mice (29 p110αFLOX and 20 p110αDEL) were distributed in 10 cages per genotype (n = 10) and male mice (22 p110αFLOX and 24 p110αDEL) mice were distributed in 12 cages per genotype (n = 12). Data are presented as mean ± SEM. Statistical analysis: unpaired two-tailed t test. *p < 0.05; **p < 0.01
