Table 1 Maximum likelihood estimates and 95% confidence intervals (CI)
From: Age-specific differences in the dynamics of protective immunity to influenza
Subtype | Parameter | MLE [95% CI] | |
|---|---|---|---|
H3N2 | Long-term boost | ζ adults,s | 0.0 [0.0, 0.03] |
ζ children,s | 0.04 [0.02, 0.07] | ||
Weight of HI-correlated immunity | ψ adults,s | 0.0 [0.0, 0.2] | |
ψ children,s | 1.0 [0.8, 1.0] | ||
50% protective titer | TP50children,s | 44 [29,74] | |
Half-life non-HI-correlated immunity | from wnonspecific, adults,s | 4.1y [3.2, 5.5] | |
Daily within-household transmission rate | ω s | 0.05 [0.02, 0.11] | |
H1N1pdm09 | Long-term boost | ζ adults,s | 0.06 [0.05, 0.07] |
ζ children,s | 0.04 [0.02, 0.07] | ||
Weight of HI-correlated immunity | ψ adults,s | 0.10 [0.07, 0.12] | |
ψ children,s | 1.0 [0.8, 1.0] | ||
50% protective titer | TP50adults,s | 8 [1,12] | |
TP50children,s | 15 [8,25] | ||
Half-life non-HI-correlated immunity | From wnonspecific, adults,s | 4.0y [3.1, 5.2] | |
Daily within-household transmission rate | ω s | 0.06 [0.03, 0.09] |
