Fig. 6
From: RNA G-quadruplex is resolved by repetitive and ATP-dependent mechanism of DHX36

Annealing of G4 to complementary cis-strand depends on successful unfolding of G4. a Schematic of cis-annealing assay. ATP-dependent G4 resolving activity of DHX36 may result in annealing or refolding of G4. b FRET histograms taken at RNA-only (gray), DHX36-bound (blue), ATP added (orange) and SDS applied (dark red) for DHX36 and three mutants. c smFRET traces taken for each construct