Table 1 Summary of mouse phenotypes of lung tumors and lungs
From: JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression
Genotype | No. | Age (Month) | The percent (%) of phenotypes in mouse lungs | |||||
|---|---|---|---|---|---|---|---|---|
SCC-DS | SCC | SCC-DS + SCC | AD-DS | AD | AD-DS + AD | |||
Lkb1 d/d | 56 | 11–14 | 25.0 | 16.1 | 32.8 | 16.1 | 37.5 | 53.6 |
Pten d/d | 12 | 12–13 | 0 | 0 | 0 | 16.7 | 8.3 | 25.0 |
P53 d/d | 10 | 12–13 | 0 | 0 | 0 | 10.0 | 10.0 | 20.0 |
Mig6 d/d | 12 | 9 | 0 | 0 | 0 | 8.3 | 0 | 8.3 |
Kras G12D | 8 | 1 | 0 | 0 | 0 | 100 | 37.5 | 100 |
Smad4 d/d | 9 | 11–13 | 0 | 0 | 0 | 0 | 0 | 0 |
WT | 25 | 1–14 | 0 | 0 | 0 | 4.0 | 0 | 4.0 |
