Fig. 8
From: Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung

Schematic diagram illustrating different collagens in the primary tumor and metastatic microenvironment and their regulation of the metastatic cascade. Airway smooth muscle cells are a collagen III rich niche for metastatic colonization of bladder cancer cells expressing CD167a, and Stat3 is a downstream target for abrogating these collagen III/CD167a-driven metastatic foci