Fig. 10 | Nature Communications

Fig. 10

From: Antidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler

Fig. 10The alternative text for this image may have been generated using AI.

Pharmacological efficacy and MOA of OPC-163493. a Pharmacologically effective animal models and expected target patient population of OPC-163493. OPC-163493 is expected to be applicable to a wide variety of hyperglycemic conditions besides type 2 DM, from type 1 DM to severe insulin resistance syndrome through its insulin-independent efficacy. b MOA of OPC163493 blood glucose-lowering effect. GLUT2 facilitated glucose transporter, type2/SLC2A2. This illustration was designed by N.K. and created by Heart-full Kawauchi Co. Ltd. (Tokushima, Japan) according to N.K.’s request as our original image

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