Table 1 Subjects characteristics included in the study

		Total	NP	PNR	PR	P-value
Total subjects		27	10	10	7
Age donor	Mean [min–max]	30 [15–47]	26 [15–47]	33 [17–44]	31 [20–42]	0.2
Age recipient	Mean [min–max]	12 [1–19]	13 [8–19]	10 [3–19]	11 [1–17]	0.3
Gender donor	Male/female	14/13	7/3	5/5	2/5	0.2
Gender recipient	Male/female	16/11	5/5	6/4	5/2	0.7
Donor source	Cadaver	13	6	4	3
Donor source	Living/related	14	4	6	4	0.6
Race recipient	Caucasian	12	2	6	4
	AA	6	4	1	1	0.2
	Asian	1	0	0	1
	Other	8	4	3	1
Immunosuppression	Steroid-based	13	6	4	3
Immunosuppression	Steroid-free	14	4	6	4	0.6
HLA mismatch	Mean [min–max]	4 [1–6]	4 [3–6]	4 [1–6]	4 [2–6]	0.8
Cause of ESRD	Non-immune structural mediated	4	2	2	0	0.6
	Other/unknown	13	5	5	3
	Reflux	10	3	3	4
Rejection time (months)	Mean [min–max]				12.5 [6.0, 24.0]
DSA		2	0	1	1	-

There were no significant differences for any of the donor and recipient characteristics by clinical outcome, including HLA mismatch and end-stage renal disease (ESRD) that was classified in three main groups: Non-immune structural mediated (polycystic kidney disease and aplastic/hypoplastic/dysplastic kidneys), Reflux (obstructive uropathy, pyelonephritis/interstitial nephritis and reflux nephropathy) and other/unknown (focal segmental glomerulosclerosis, cystinosis, hemolytic uremic syndrome, cortical necrosis, other and unknown). Class I DSA was developed in one individual in the PNR and also was found at time 0 in another individual in the PR group

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