Fig. 2 | Nature Communications

Fig. 2

From: Near physiological spectral selectivity of cochlear optogenetics

Fig. 2

Acoustic, optogenetic, and electric activation of the auditory system. ad Monotonicity indices (MI) normalized to the maximum bin for acoustic stimulation in non-injected animals (a), optogenetic stimulation in virus-injected animals (b), monopolar (c), and bipolar electric stimulation in non-injected animals (d). Dashed lines mark a monotonicity index of 0.5, above which units are considered as monotonic. eh Firing rates of multi-units as a function of stimulus intensity (thin, transparent lines) and average per animal and stimulus (solid lines) for acoustic (e), optogenetic (f), monopolar (g), and bipolar (h) electric stimulation. i Distribution of dynamic ranges (DRs) per multi-unit in dB (SPL), dB (mW), and dB (µA). j DRs of averaged multi-units per animal and stimulus, units as in (e). k Maximum strength of response that could be evoked by any stimulus modality. Data in (i), (j), and (k) is displayed as mean ± s.d. Stars indicate statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001), based on one-way ANOVA and post-hoc pairwise comparison. Only significant differences are indicated. Source data of all panels is provided as a source data file

Back to article page