Fig. 3
From: CUT&Tag for efficient epigenomic profiling of small samples and single cells
Reproducibility and efficiency of CUT&Tag. a Hierarchically clustered correlation matrix of CUT&Tag replicates (R1 and R2) and with CUT&RUN and ChIP-seq profiling for the H3K4me1 histone modification. The same antibody was used in all experiments. Pearson correlations were calculated using the log2-transformed values of read counts split into 500 bp bins across the genome. b Efficiency of peak-calling between methods. Mitochondrial reads were removed from datasets from each method profiling the H3K4me2 histone modification. The remaining read counts were downsampled to varying depths, and then used to call peaks using MACS2. The summed number of reads falling within called peaks in each dataset was plotted. Source data are available in the Source Data file
