Fig. 7 | Nature Communications

Fig. 7

From: Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures

Fig. 7

Complete deconvolution pipeline reveals bias when fractions are compared to blood counts. The results of the pipeline for dataset GSE20300 (a), GSE77434 (b), and E-MTAB-6413 (c). d Simulation dataset where cell types had different RNA content. In the middle, predicted proportions are compared against fraction of cell types RNA in the sample. On the right, predicted proportions are compares against actual cell type counts

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