Fig. 2
From: Integrating Hi-C and FISH data for modeling of the 3D organization of chromosomes
The modeling results of human Chromosome 21 (Chr21). a The TAD-level resolution 3D structure of Chr21 calculated by GEM-FISH, where each dot represents the center of a TAD. b The final 3D structure of Chr21 reconstructed by GEM-FISH. The visualization in (a) and (b) was performed using UCSF Chimera61. c, d The relative error matrices of the TAD-level resolution models computed by GEM-FISH using both Hi-C and FISH data, and by GEM using only Hi-C data, respectively. e, f The relative error matrices of the final models computed by GEM-FISH using both Hi-C and FISH data, and GEM using only Hi-C data, respectively
