Fig. 4 | Nature Communications

Fig. 4

From: Integrating Hi-C and FISH data for modeling of the 3D organization of chromosomes

Fig. 4

The modeling results of GEM-FISH for the human X-Chromosome (including both active state ChrXa and inactive state ChrXi). a, b Visualization of the final 3D models of ChrXa (a) and ChrXi (b) in UCSF Chimera61. (c) Comparison of the compactness of TADs between the 3D models of active (ChrXa) and inactive (ChrXi) states of human X-Chromosome. N = 40 TADs for both Chrs Xa and Xi. *p-value < 10−13, one-tailed Wilcoxon rank-sum test. d, e The assignment of TADs of ChrXa (d) and ChrXi (e) to the A/B compartments. f, g Projection of the 3D convex hull plots of the A and B compartments of ChrXa (f) and ChrXi (g) to the XZ plane. For the boxplots, the top and bottom lines of each box represent the 75th and 25th percentiles of the samples, respectively. The line inside each box represents the median of the samples. The upper and lower lines above and below the boxes are the whiskers

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