Fig. 2

Heterogeneous surface expression of killer-like receptors and GPR56 in CD4⁺ T cells. a Exemplary dot plots of KLRB1, KLRG1, KLRF1, GPR56, TIGIT, and PD-1 surface expression in gated CD4⁺ T_N, T_CM, T_EM, and T_EMRA cells from blood of healthy donors. b Comparison of KLRB1-, KLRG1-, KLRF1-, and GPR56-positive cell frequencies obtained either from single-cell gene expression analysis (mRNA, n = 209 (T_N), 260 (T_CM), 396 (T_EM), and 248 (T_EMRA) from four donors) or flow cytometric analysis (protein, n = 5) within CD4⁺ T_N, T_CM, T_EM, and T_EMRA cells. Data are shown as individual scatter plots with median. Statistical analysis by two-way ANOVA and Sidakʼs multiple comparison test. **p < 0.01, ***p < 0.001