Table 2 Scope of the metal-free hydroacylation of alkenesa

From: A redox-neutral synthesis of ketones by coupling of alkenes and amides

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  1. aReaction conditions: 1 (0.2 mmol), Tf2O (0.22 mmol), 2-F-Py (0.22 mmol), alkene 2 (0.4 mmol) in DCM (0.1 M) at 0 °C for 2 h and warmed up to room temperature for 12 h under argon; isolated yield after chromatography
  2. bCH3CN was used instead of DCM
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