Fig. 5
Prevalence of stress resistance genes in Lm clones. We analyzed a set of 2928 genome sequences of non-redundant Lm isolates collected from 2015 to 2018 in the context of the French surveillance of listeriosis. Major CCs representing individually at least 0.5% of all the isolates of the study are shown. Prevalence of genes known to be involved in Lm stress resistance is shown per clone21. The blue intensity reflects the percentages of isolates harboring the considered genes. Clones are sorted according to their clinical frequency, represented with a red gradient at the top of the graph. Clones analyzed with in vivo and in vitro experiments in this study (i.e., CC1, CC2, CC4, CC6, CC9, and CC121) are highlighted with orange rectangles. Genes are sorted according to their function. Orange arrows indicate genes that are enriched in clones having a low clinical frequency. LGI: Listeria genomic island. SSI: Stress survival islet. BC: Benzalkonium choride
