Fig. 8 | Nature Communications

Fig. 8

From: Feed-forward regulation adaptively evolves via dynamics rather than topology when there is intrinsic noise

Fig. 8

The two TFs in an AND-gated diamond propagate the signal at different speeds. Expression of the two TFs in one representative genotype from the one high-fitness evolutionary replicate in Fig. 7b that evolved an AND-gated isolated diamond is shown. Both the slow TF and the fast TF are encoded by three gene copies, shown separately in color, with the total for each TF in thick black. The expression of one TF plateaus faster than that of the other; this is characteristic of the AND-gated diamond motif, and leads to the same functionality as the AND-gated C1-FFL

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