Fig. 1 | Nature Communications

Fig. 1

From: Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells

Fig. 1

RPL10 R98S and RPL10 WT cells show distinct ribosome footprinting signatures. a Outline of the study design. b Distribution of the length of ribosome footprints (RPF, ribosome-protected mRNA fragments). c Left: triplet periodicity of ribosome footprinting reads; right: lack of triplet periodicity for mRNA-sequencing reads. The fraction of reads assigned to each of the three frames of translation is reported for each read length. d Metagene profiles of RPF densities around the start and stop codons (indicated by 0). The number of RPFs per position was averaged over all transcripts and normalized for the total number of mapped RPFs. e Principal component analysis based on normalized RPF counts

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