Fig. 2 | Nature Communications

Fig. 2

From: Phosphorylated lipid-conjugated oligonucleotide selectively anchors on cell membranes with high alkaline phosphatase expression

Fig. 2

Hydrophobicity-dependent cell membrane adhesion of lipid-conjugated oligonucleotides. a Schematic illustration of the structure of C6-DNA, C9-DNA, C12-DNA and C15-DNA with different alkyl chain lengths in lipid tails. b HPLC chromatograms of DNA, C6-DNA, C9-DNA, C12-DNA and C15-DNA. c Flow cytometry of HepG2 cells treated with 1 μM TAMRA-labeled DNA, C6-DNA, C9-DNA, C12-DNA or C15-DNA. d Confocal fluorescence microscopy imaging of HepG2 cells treated with 1 μM TAMRA-labeled C6-DNA, C9-DNA, C12-DNA or C15-DNA. Scale bar is 10 μm

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