Fig. 1
From: Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA
The cytosolic domain of IncA folds into a non-canonical α-helical bundle. a Schematic diagram of C. trachomatis IncA domain organization. Transmembrane helices (TMH) were predicted using the HMMTOP server50. The stable core encompassing residues 87–246 (IncA87–246) was identified by limited proteolysis of the cytosolic domain as described8. b Ribbon diagram of IncA87–246 with α-helices and random coiled linkers colored in cyan and red, respectively. c, d Two rotated views of IncA87–246, orthogonal to the representation in b, with α-helices shown as cylinders. c highlights the segmented structure of the helix HB, while d shows the relative angle between helices HC and HD
