Fig. 1
Single-nucleus RNA-seq interrogation of the human kidney. a Overview of kidney tissue processing methods tested for nuclei isolation and snDrop-seq. b UMAP visualization of 17,659 single nuclei (15 individuals, Supplementary Data 4) passing QC filtering (Supplementary Fig. 2a). Source data are provided as a Source Data file. c Schematic of a juxtamedullary nephron36 showing relevant cell types and associated vasculature. d Table of single-nucleus clusters shown in (b), indicating associated cell-type annotations, number of nuclei per cluster and relative origination from samples encompassing the cortex, medulla or both (Supplementary Data 6 and provided as a Source Data File). UMAP uniform manifold approximation and projection
