Fig. 4
From: AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

GluA2 Molecular dynamic stimulations predict reduced mobility at the agonist binding site. Root Mean Square Deviation (RMSD) of the GluA2 Glutamate binding pocket (GLU) amino acids along the simulated time for the wild-type protein (top left) and GRIA2 mutants (a–i). In all panels the color code is: chain A (blue/cyan), chain B (black/yellow), chain C (red/orange), and chain D (light/dark green). Thicker lines indicate running averages over 100 samples