Fig. 10 | Nature Communications

Fig. 10

From: Adult stem cell deficits drive Slc29a3 disorders in mice

Fig. 10The alt text for this image may have been generated using AI.

Schematic representation of disease pathogenesis in Slc29a3−/− mice. Molecular, cellular and tissue defects in Slc29a3−/− mice are depicted. Broken lines or arrows indicate inhibitory pathways, and thick arrows indicate the stimulatory pathways occurring in Slc29a3−/− mice. Phosphorylation statuses of AMPK, mTOR, and ULK in Slc29a3−/− cells are shown (P, phosphorylated, yellow circle; NP, non-phosphorylated, green circle). CFU, colony-forming unit; E, erythroid; meg, megakaryocyte; G, granulocyte; M, macrophage; GM, granulocyte/macrophage; GEMM, granulocyte/erythrocyte/macrophage/megakaryocyte

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