Fig. 3
From: Non-coding variability at the APOE locus contributes to the Alzheimer’s risk
Forest plot of haplotypes contributing to AD after controlling for APOE genotypes. Forest plot with values of effect size obtained from independent datasets or meta-results denoted by rectangles and diamonds, respectively. For each row representing the independent dataset, lines indicate 95% confidence intervals, and sizes of rectangles are proportional to the weights in the meta-analysis. a, b PVRL2 alpha and APOC1 gamma haplotypes were associated with AD in an APOE genotype-independent manner (p-values shown are for Han and Eskin’s random effects model). c, d Association results of extended minor haplotypes delta and epsilon after controlling for APOE-ε4 genotypes (p-values are for Han and Eskin’s random effects model). AD Alzheimer’s disease, RE random effects, RE2 Han and Eskin’s random effects model
