Fig. 5
From: Chemical logic of MraY inhibition by antibacterial nucleoside natural products
Structurally diverse moieties occupy the uridine-adjacent binding pocket in MraYAA. a Carbacaprazamycin (magenta), b muraymycin D2 (orange), c capuramycin (yellow), d 3′-hydroxymureidomycin A (green), e tunicamycin (slate) binding interactions at the uridine-adjacent pocket. Residues labeled in black and blue form side chain and backbone interactions with the inhibitor, respectively. Hydrogen bonds are represented by black dashed lines. Residue numbering is shown for MraYAA except in e, which shows residue numbering for MraYCB with the corresponding residues in MraYAA provided in parentheses
