Fig. 2 | Nature Communications

Fig. 2

From: Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data

Fig. 2The alternative text for this image may have been generated using AI.

Variant selection flowchart. Flowchart outlining variant selection for high-depth sequencing validation experiments. Candidate DNMs from trio exome sequencing were used to select candidate mosaic DNMs in the proband (blue) as well as ‘low level’ mosaic variants in a parent (light red) for validation; candidate inherited variants were used to select ‘high level’ mosaic variants in a parent (dark red) for ultrahigh-depth sequencing

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