Table 2 KM and Kcat values from non-linear regression of the data in Fig. 2c
From: Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP
INCENP | Kcat (103 s−1) | Km(peptide) (μM) | |
|---|---|---|---|
AURKB | w.t. | 50.8 ± 1.5 | 10.8 ± 1.5 |
S893A | 50.1 ± 0.9 | 75.5 ± 3.6 | |
S894A | 32.9 ± 0.7 | 90.6 ± 4.7 | |
W897A | 51.9 ± 1.2 | 47.1 ± 3.2 | |
AURKC | w.t. | 48.8 ± 2.3 | 18.7 ± 3.6 |
S893A | 46.3 ± 1.4 | 83.0 ± 6.1 | |
S894A | 38.8 ± 0.6 | 83.0 ± 3.1 | |
W897A | 41.8 ± 0.9 | 25.1 ± 1.9 |
