Table 3 Modelled performance of the methylation-, count-, size- and combined analyses in the screening cohort by target-capture bisulfite sequencing
From: Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases
| Â | Sensitivity (%) | Specificity (%) | PPV (%) |
|---|---|---|---|
Methylation based | 97.1 | 99.1 | 15.9 |
Count based | 97.1 | 98.7 | 11.2 |
Size based | 97.1 | 96.6 | 4.7 |
Combined count and size based | 97.1 | 99.1 | 16.6 |
Combined methylation, count and size based | 97.1 | 99.7 | 35.1 |
