Fig. 7
Collated marker expression in hepatic progenitor populations. Heatmaps of selected marker expression in populations identified in this study with different cohorts of liver progenitor-like cells, biliary epithelial cells (BECs) and primary hepatocytes. Shown is gene expression patterns of publicly available sequencing data from GEO (https://www.ncbi.nlm.nih.gov/geo/) or literature mined. Bulk RNA-seq data sets, include reprogrammed human hepatic liver progenitor cells (hepLPCs-Heps, GSE105019) and primary hepatocytes (pHs, GSE105019) from Fu et al.16 and mouse hepatocyte-derived proliferative ducts (HepPD, Tarlow et al. 2015) and biliary-derived proliferative ducts ((BilPD) (GSE55552), Tarlow et al. 2015)8. ScRNA-seq data sets, include human BECs (GSE115469) from MacParland et al.23. Expression graded as high (red) to low (blue) relative to individual data sets
