Fig. 3
Requirement for coinfection poses a barrier to establishing an infection in a population of cells. To define the impact of IVGs on the ability of a virus to establish infection in a population of cells, the probability that a population of 106 cells became infected by a given number of virions was calculated. a The percentage chance of at least one cell containing eight genome segments following delivery of virions was calculated for each PP and across a range of MOIs. b The MOI that led to 50% of cell populations becoming infected (ID50) was plotted as a function of PP, where complementation was possible (solid line), and where only complete viral genomes could initiate infection (dashed line). IVGs = incomplete viral genomes. Source data are provided as a Source Data file
