Fig. 4 | Nature Communications

Fig. 4

From: Multiple origins of prokaryotic and eukaryotic single-stranded DNA viruses from bacterial and archaeal plasmids

Fig. 4

Relationships between Superfamily 3 helicases and AAA+ ATPases. a Superfamily 3 helicase and AAA+ ATPase domains clustered by their pairwise similarity using CLANS. In total, 3854 sequences were clustered with CLANS (CLANS P-value ≤ 5e−09). Groups of unclassified CRESS-DNA viruses are referred to as CRESSV1 through CRESSV6 (ref. 53). b A proposed evolutionary scenario for the origin and evolution of viral Superfamily 3 helicases. Abbreviations: SF3, superfamily 3 helicase domain; HUH, HUH superfamily nuclease domain; OBD, origin-binding domain; HGT, horizontal gene transfer; RHR, rolling-hairpin replication

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