Fig. 4 | Nature Communications

Fig. 4

From: Proteogenomic landscape of squamous cell lung cancer

Fig. 4

Tertiary lymph nodes (TLN) are enriched in the Inflamed subtype and are associated with better outcomes. a, b Proteomic subtypes are not associated with overall or recurrence-free survival. c TLN, indicated by red boxes, are observable in H&E stained slides under low magnification. d TLN can be observed in all three proteomic subtypes but are enriched in Inflamed (Cochran-Mantel-Haenszel P = 0.036). The height of each rectangle is proportional to the TLN score in a given subtype, and the width of each column is proportional to the number of samples in each subtype. e, f Presence of TLN provided a benefit to both overall and recurrence-free survival. g, h Immunohistochemical staining shows TLN primarily consist of CD20+ memory B-cells

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